Reactome | Negative regulation by 'KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]'

Schema > NegativeRegulation > Entries

activeUnit	[EntityWithAccessionedSequence:R-COV-9705293] 6 [endoplasmic reticulum-Golgi intermediate compartment membrane] - Severe acute respiratory syndrome coronavirus 2
created	[InstanceEdit:9757523] Shamovsky, Veronica, 2021-11-01
dbId	9757522
displayName	Negative regulation by 'KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]'
goBiologicalProcess	[GO_BiologicalProcess:2266337] symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
regulatedEntity	[Reaction:R-HSA-9768142] Dimerized phospho-IRF3, IRF7 is transported to the nucleus - Homo sapiens
regulator	[Complex:R-HSA-9705285] KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]
schemaClass	NegativeRegulation

(regulation)	[RegulationReference:9765933] Negative regulation by 'KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]' Evasion of Type I Interferon by SARS-CoV-2
(regulatedBy)	[Reaction:R-HSA-9768142] Dimerized phospho-IRF3, IRF7 is transported to the nucleus

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