Reactome | p-Y FLT3 fusions:GRB2:GAB2 [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9703426] protein tyrosine kinase activity of p-Y FLT3 fusions:GRB2:GAB2 [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-9703438] FLT3 fusions phosphorylate GAB2 - Homo sapiens
created	[InstanceEdit:9703348] Rothfels, Karen, 2020-10-06
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9703352
disease	[Disease:1500689] cancer
displayName	p-Y FLT3 fusions:GRB2:GAB2 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-HSA-508239] GAB2 [cytosol] [Complex:R-HSA-9703378] p-Y FLT3 fusion dimers:GRB2 [cytosol]
inDisease	true
isChimeric	false
maxDepth	5
name	p-Y FLT3 fusions:GRB2:GAB2
producedByEvent	[Reaction:R-HSA-9703440] FLT3 fusions:GRB2 bind GAB2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9703352

(input)	[Reaction:R-HSA-9703438] FLT3 fusions phosphorylate GAB2
(physicalEntity)	[CatalystActivity:9703426] protein tyrosine kinase activity of p-Y FLT3 fusions:GRB2:GAB2 [cytosol]
(output)	[Reaction:R-HSA-9703440] FLT3 fusions:GRB2 bind GAB2

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