Reactome | FLT3 fusion proteins [cytosol]

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FLT3 fusion proteins [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-9703433] Ligand-independent dimerization of FLT3 fusion proteins - Homo sapiens [Reaction:R-HSA-9703433] Ligand-independent dimerization of FLT3 fusion proteins - Homo sapiens
created	[InstanceEdit:9703346] Rothfels, Karen, 2020-10-06
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9703345
disease	[Disease:1500689] cancer
displayName	FLT3 fusion proteins [cytosol]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-9703323] TRIP11(2-1724)-FLT3(594-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9703311] ZMYM2(1-1057)-FLT3(586-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9703310] ZMYM2(1-1059)-FLT3(594-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9703314] MYO18A(1-1462)-FLT3(595-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9703302] ETV6(1-154)insGSFILG-p-6Y-FLT3(573-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9703320] ETV6(1-336)insGCS-FLT3(573-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9703307] ETV6(1-384)-FLT3(573-993) fusion [cytosol] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-9703315] ETV6(1-301)-FLT3(574-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9697944] ETV6(1-384)-FLT3(569-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9703322] GOLGB1(1-2893)-FLT3(591-993) fusion [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9703316] SPTBN1(2-159)-FLT3(570-993) fusion [cytosol] - Homo sapiens
inDisease	true
literatureReference	[LiteratureReference:9703256] A novel TRIP11-FLT3 fusion in a patient with a myeloid/lymphoid neoplasm with eosinophilia [LiteratureReference:9604770] Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3 [LiteratureReference:9703263] A novel t(3;13)(q13;q12) translocation fusing FLT3 with GOLGB1: toward myeloid/lymphoid neoplasms with eosinophilia and rearrangement of FLT3?
maxDepth	2
name	FLT3 fusion proteins
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9703345

Referrals

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[Reaction:R-HSA-9703433] Ligand-independent dimerization of FLT3 fusion proteins

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