Reactome | MYO18A(1-1462)-FLT3(595-993) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-9703345] FLT3 fusion proteins [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9703350] MYO18A(1-1462)-FLT3(595-993) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9703350] MYO18A(1-1462)-FLT3(595-993) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9703321] Rothfels, Karen, 2020-10-06
crossReference	[DatabaseIdentifier:12021115] Mondo:0004643
dbId	9703314
disease	[Disease:1500689] cancer [Disease:9688871] myeloid leukemia
displayName	MYO18A(1-1462)-FLT3(595-993) fusion [cytosol]
endCoordinate	1462
hasModifiedResidue	[FragmentInsertionModification:9703291] Insertion of residues 595 to 993 at 1463 from UniProt:P36888 FLT3
inDisease	true
literatureReference	[LiteratureReference:9703169] Two myeloid leukemia cases with rare FLT3 fusions
maxDepth	1
name	MYO18A(1-1462)-FLT3(595-993) fusion Unconventional myosin-XVIIIa MY18A_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:Q92614] UniProt:Q92614 MYO18A
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9703314
startCoordinate	1

(hasCandidate)	[CandidateSet:R-HSA-9703345] FLT3 fusion proteins [cytosol]
(hasComponent)	[Complex:R-HSA-9703350] MYO18A(1-1462)-FLT3(595-993) fusion dimer [cytosol]

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