Reactome | ETV6(1-384)-FLT3(573-993) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-9703345] FLT3 fusion proteins [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9703371] ETV6(1-384)-FLT3(573-993) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9703371] ETV6(1-384)-FLT3(573-993) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9703321] Rothfels, Karen, 2020-10-06
crossReference	[DatabaseIdentifier:12021115] Mondo:0004643
dbId	9703307
disease	[Disease:9688871] myeloid leukemia
displayName	ETV6(1-384)-FLT3(573-993) fusion [cytosol]
endCoordinate	384
hasModifiedResidue	[FragmentInsertionModification:9703293] Insertion of residues 573 to 993 at 385 from UniProt:P36888 FLT3
inDisease	true
literatureReference	[LiteratureReference:9703169] Two myeloid leukemia cases with rare FLT3 fusions
maxDepth	1
name	ETV6(1-384)-FLT3(573-993) fusion Transcription factor ETV6 ETV6_HUMAN EF1
referenceEntity	[ReferenceGeneProduct:uniprot:P41212] UniProt:P41212 ETV6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9703307
startCoordinate	1

(hasCandidate)	[CandidateSet:R-HSA-9703345] FLT3 fusion proteins [cytosol]
(hasComponent)	[Complex:R-HSA-9703371] ETV6(1-384)-FLT3(573-993) fusion dimer [cytosol]

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