Reactome | Active ALK:SHC1 [plasma membrane]

Schema > Complex > Entries

Active ALK:SHC1 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:9700104] protein tyrosine kinase activity of Active ALK:SHC1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-9700175] Active ALK phosphorylates SHC1 - Homo sapiens
created	[InstanceEdit:9699984] Rothfels, Karen, 2020-09-14
dbId	9699970
displayName	Active ALK:SHC1 [plasma membrane]
hasComponent	[CandidateSet:R-HSA-9850879] Active ALK dimer [plasma membrane] [DefinedSet:R-HSA-1169480] SHC1-2,SHC1-3 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-9699970] Active ALK:SHC1 [plasma membrane] - Mus musculus [Complex:R-RNO-9699970] Active ALK:SHC1 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-9699970] Active ALK:SHC1 [plasma membrane] - Canis familiaris [Complex:R-BTA-9699970] Active ALK:SHC1 [plasma membrane] - Bos taurus [Complex:R-SSC-9699970] Active ALK:SHC1 [plasma membrane] - Sus scrofa [Complex:R-XTR-9699970] Active ALK:SHC1 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-9699970] Active ALK:SHC1 [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:9699620] ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation
maxDepth	6
modified	[InstanceEdit:9850952] Rothfels, Karen, 2023-10-12
name	Active ALK:SHC1
producedByEvent	[Reaction:R-HSA-9700154] Active ALK binds SHC1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9699970
updateTrackers	[UpdateTracker:9906365] Update Tracker - [Complex:9699970] Active ALK:SHC1 [plasma membrane] - v87:[add_removeHasComponent, modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9906365] Update Tracker - [Complex:9699970] Active ALK:SHC1 [plasma membrane] - v87:[add_removeHasComponent, modifyName]
(output)	[Reaction:R-HSA-9700154] Active ALK binds SHC1
(input)	[Reaction:R-HSA-9700175] Active ALK phosphorylates SHC1
(physicalEntity)	[CatalystActivity:9700104] protein tyrosine kinase activity of Active ALK:SHC1 [plasma membrane]