Reactome | TFG(1-138)-ALK(1058-1620) fusion [cytosol]

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TFG(1-138)-ALK(1058-1620) fusion [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9702017] TFG(1-138)-ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9702017] TFG(1-138)-ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9699845] Rothfels, Karen, 2020-09-14
crossReference	[DatabaseIdentifier:12020842] Mondo:0020325 [DatabaseIdentifier:9700456] COSMIC:COSF424
dbId	9699874
disease	[Disease:9699595] anaplastic large cell lymphoma [Disease:1500689] cancer
displayName	TFG(1-138)-ALK(1058-1620) fusion [cytosol]
endCoordinate	138
hasModifiedResidue	[FragmentInsertionModification:9699849] Insertion of residues 1058 to 1620 at 139 from UniProt:Q9UM73 ALK
inDisease	true
literatureReference	[LiteratureReference:9699785] TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations [LiteratureReference:9699672] Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activity
maxDepth	1
memberOf	[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol] - Homo sapiens
modified	[InstanceEdit:9702047] Rothfels, Karen, 2020-09-28
name	TFG(1-138)-ALK(1058-1620) fusion Protein TFG TFG_HUMAN TFGs-ALK
referenceEntity	[ReferenceGeneProduct:uniprot:Q92734] UniProt:Q92734 TFG
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9699874
startCoordinate	1

Referrals

(hasMember)	[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol]
(hasComponent)	[Complex:R-HSA-9702017] TFG(1-138)-ALK(1058-1620) fusion dimer [cytosol]

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