Reactome | Maturation of spike protein

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Maturation of spike protein Show undefined attributes

authored	[InstanceEdit:9683645] Stephan, Ralf, 2020-04-08
created	[InstanceEdit:9683729] Stephan, Ralf, 2020-04-17
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9683686
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	Maturation of spike protein
edited	[InstanceEdit:9689807] D'Eustachio, Peter, 2020-05-21
eventOf	[Pathway:R-HSA-9683701] Translation of Structural Proteins - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:6677] viral protein processing
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-HSA-9683755] Spike protein gets N-glycosylated - Homo sapiens [BlackBoxEvent:R-HSA-9683663] N-glycan trimming of Spike - Homo sapiens [Reaction:R-HSA-9686790] ER-alpha glucosidases bind ER-alpha glucosidase inhibitors - Homo sapiens [Reaction:R-HSA-9683772] Trimmed spike protein binds to calnexin - Homo sapiens [Reaction:R-HSA-9683653] Spike protein gets palmitoylated - Homo sapiens [Reaction:R-HSA-9683719] Spike protein forms a homotrimer - Homo sapiens [BlackBoxEvent:R-HSA-9683764] Spike trimer translocates to ERGIC - Homo sapiens [BlackBoxEvent:R-HSA-9683648] Spike trimer glycoside chains are extended - Homo sapiens
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9683050] Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E
maxDepth	2
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Maturation of spike protein
orthologousEvent	[Pathway:R-HSA-9694548] Maturation of spike protein - Homo sapiens
precedingEvent	[BlackBoxEvent:R-HSA-9683624] mRNA2 is translated to Spike - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2020-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020-05-27
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9683686
summation	[Summation:9682954] Spike protein of SARS-Cov is subject to N-glycosylation and ...

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[Pathway:R-HSA-9683701] Translation of Structural Proteins

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