Maturation of spike protein

Stable Identifier
R-HSA-9683686
Type
Pathway
Species
Homo sapiens
Related Species
Human SARS coronavirus
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Spike protein of SARS-Cov is subject to N-glycosylation and palmitoylation. The chaperone calnexin exclusively helps with protein folding. The end product is a homotrimer (Nal et al, 2005).

Literature References
PubMed ID Title Journal Year
15831954 Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E

Nal, B, Chan, C, Kien, F, Siu, L, Tse, J, Chu, K, Kam, J, Staropoli, I, Crescenzo-Chaigne, B, Escriou, N, van der Werf, S, Yuen, KY, Altmeyer, R

J. Gen. Virol. 2005
Participants
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Event Information
Go Biological Process
Disease
Name Identifier Synonyms
severe acute respiratory syndrome 2945 SARS-CoV infection, SARS
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