Reactome | imatinib resistant KIT mutants [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[FailedReaction:R-HSA-9669859] Imatinib-resistant KIT mutants do not bind imatinib - Homo sapiens
created	[InstanceEdit:9669747] Rothfels, Karen, 2019-12-03
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9669748
disease	[Disease:1500689] cancer
displayName	imatinib resistant KIT mutants [plasma membrane]
hasMember	[EntityWithAccessionedSequence:R-HSA-9669426] KIT A829P [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669436] KIT D816E [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669460] KIT D820A [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669545] KIT T670I [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669572] KIT V654A [plasma membrane] - Homo sapiens
inDisease	true
maxDepth	2
name	imatinib resistant KIT mutants
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9669748

(input)	[FailedReaction:R-HSA-9669859] Imatinib-resistant KIT mutants do not bind imatinib
(diseaseEntity)	[EntityFunctionalStatus:9669860] loss_of_function of imatinib resistant KIT mutants [plasma membrane]

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