Reactome | FGFR2b C382R [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-2029955] FGFR2 ligand-independent mutants [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9667347] FGFR2b C382R mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9667347] FGFR2b C382R mutant dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9667335] Rothfels, Karen, 2019-11-11
crossReference	[DatabaseIdentifier:12020781] Mondo:0011962 [DatabaseIdentifier:9667341] COSMIC:COSV60638681 [DatabaseIdentifier:9667336] COSMIC:COSV60638681
dbId	9667332
disease	[Disease:2317358] endometrial cancer
displayName	FGFR2b C382R [plasma membrane]
endCoordinate	821
hasModifiedResidue	[ReplacedResidue:9667342] L-cysteine 382 replaced with L-arginine
inDisease	true
literatureReference	[LiteratureReference:9667337] Activating FGFR2-RAS-BRAF mutations in ameloblastoma
maxDepth	1
name	FGFR2b C382R
referenceEntity	[ReferenceIsoform:uniprot:P21802-3] UniProt:P21802-3 FGFR2
referenceType	ReferenceIsoform
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9667332
startCoordinate	22

(hasComponent)	[Complex:R-HSA-9667347] FGFR2b C382R mutant dimer [plasma membrane]
(hasCandidate)	[CandidateSet:R-HSA-2029955] FGFR2 ligand-independent mutants [plasma membrane]

Cite Us!