Reactome | p-6Y-ERBB2 S310F [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

p-6Y-ERBB2 S310F [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9665383] Orlic-Milacic, Marija, 2019-10-30
crossReference	[DatabaseIdentifier:12021327] Mondo:0003212 [DatabaseIdentifier:9665339] COSMIC:COSM1666868 [DatabaseIdentifier:9665343] COSMIC:COSV54062198
dbId	9665379
disease	[Disease:1500689] cancer [Disease:9630851] gallbladder adenocarcinoma [Disease:1500576] breast cancer [Disease:9667181] cervical adenocarcinoma [Disease:2317358] endometrial cancer [Disease:2328198] pancreatic cancer [Disease:9630864] pancreatic ductal adenocarcinoma [Disease:9667179] bladder adenocarcinoma [Disease:9667180] invasive bladder transitional cell carcinoma [Disease:9667178] bladder squamous cell carcinoma [Disease:2327989] bile duct carcinoma [Disease:9631134] cervical squamous cell carcinoma [Disease:1248674] large intestine cancer [Disease:8853117] lung adenocarcinoma [Disease:1500575] ovarian cancer [Disease:1655480] salivary gland cancer [Disease:6802273] skin melanoma [Disease:2328001] skin squamous cell carcinoma [Disease:2328199] basal cell carcinoma [Disease:1614291] rhabdomyosarcoma [Disease:1500687] stomach cancer [Disease:2327997] pharynx cancer [Disease:9667177] nasal cavity carcinoma
displayName	p-6Y-ERBB2 S310F [plasma membrane]
endCoordinate	1255
hasModifiedResidue	[ReplacedResidue:9665345] L-serine 310 replaced with L-phenylalanine [ModifiedResidue:1248700] O4'-phospho-L-tyrosine at 1023 [ModifiedResidue:1248685] O4'-phospho-L-tyrosine at 1139 [ModifiedResidue:1248708] O4'-phospho-L-tyrosine at 1196 [ModifiedResidue:1248692] O4'-phospho-L-tyrosine at 1221 [ModifiedResidue:1248701] O4'-phospho-L-tyrosine at 1222 [ModifiedResidue:1248689] O4'-phospho-L-tyrosine at 1248
inDisease	true
literatureReference	[LiteratureReference:9665365] Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2
maxDepth	1
memberOf	[CandidateSet:R-HSA-9665392] p-6Y-ERBB2 ECD mutants [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9667329] Rothfels, Karen, 2019-11-11
name	p-6Y-ERBB2 S310F p-6Y-ERBB2 Ser310Phe
referenceEntity	[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9665379
startCoordinate	23

Referrals

(hasMember)

[CandidateSet:R-HSA-9665392] p-6Y-ERBB2 ECD mutants [plasma membrane]