Reactome | ERBB2 T798M:ERBIN:HSP90:CDC37 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[FailedReaction:R-HSA-9665311] ERBB2 T798M does not bind afatinib - Homo sapiens
created	[InstanceEdit:9665301] Orlic-Milacic, Marija, 2019-10-30
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9665313
disease	[Disease:1500689] cancer
displayName	ERBB2 T798M:ERBIN:HSP90:CDC37 [plasma membrane]
hasComponent	[Complex:R-HSA-1225828] CDC37 [cytosol] [EntityWithAccessionedSequence:R-HSA-9646825] ERBB2 T798M [plasma membrane] [EntityWithAccessionedSequence:R-HSA-1358718] ERBIN [plasma membrane] [Complex:R-HSA-1221657] HSP90 [cytosol]
inDisease	true
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	3
name	ERBB2 T798M:ERBIN:HSP90:CDC37
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9665313

(input)	[FailedReaction:R-HSA-9665311] ERBB2 T798M does not bind afatinib
(diseaseEntity)	[EntityFunctionalStatus:9665310] loss_of_function of ERBB2 T798M:ERBIN:HSP90:CDC37 [plasma membrane]

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