Reactome | OGG1 S326C is oxidized

Schema > Reaction > Entries

authored	[InstanceEdit:9656251] Orlic-Milacic, Marija, 2019-07-30
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9658812] Orlic-Milacic, Marija, 2019-08-19
dbId	9658813
disease	[Disease:1500689] cancer
displayName	OGG1 S326C is oxidized
edited	[InstanceEdit:9663704] Orlic-Milacic, Marija, 2019-10-10
eventOf	[Pathway:R-HSA-9656256] Defective OGG1 Substrate Processing - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9658769] OGG1 S326C [nucleoplasm] [SimpleEntity:R-ALL-3785707] ROS [nucleoplasm]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9658804] hOGG1-Cys326 variant cells are hypersensitive to DNA repair inhibition by nitric oxide [LiteratureReference:9658795] 8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes [LiteratureReference:9658781] OGG1 Mutations and Risk of Female Breast Cancer: Meta-Analysis and Experimental Data
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	OGG1 S326C is oxidized
output	[EntityWithAccessionedSequence:R-HSA-9658815] SOH-C326-OGG1 S326C [nucleoplasm]
releaseDate	2019-12-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9663702] Vlahopoulos, Spiros, 2019-10-02 [InstanceEdit:9663703] Boldogh, Istvan, 2019-10-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9658813
summation	[Summation:9658816] OGG1 S326C is a frequent genetic polymorphism, present in mo...

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