Reactome | KRAS K117N [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9653094] Rothfels, Karen, 2019-07-09
crossReference	[DatabaseIdentifier:12021095] Mondo:0002334 [DatabaseIdentifier:9653065] COSMIC:COSM30612 [DatabaseIdentifier:9653057] COSMIC:COSV55545304 [DatabaseIdentifier:9653063] COSMIC:COSV55504752
dbId	9653095
disease	[Disease:4791250] colorectal cancer [Disease:6802336] hematologic cancer
displayName	KRAS K117N [plasma membrane]
endCoordinate	186
hasModifiedResidue	[ReplacedResidue:9653030] L-lysine 117 replaced with L-asparagine
inDisease	true
literatureReference	[LiteratureReference:9653003] Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - implications for personalised cancer medicine
maxDepth	1
memberOf	[CandidateSet:R-HSA-9651281] RAS GAP mutants [plasma membrane] - Homo sapiens
name	KRAS K117N
referenceEntity	[ReferenceGeneProduct:uniprot:P01116] UniProt:P01116 KRAS
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9653095
startCoordinate	1

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