KRAS K117N [plasma membrane]

Stable Identifier
R-HSA-9653095
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
20147967 Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - implications for personalised cancer medicine

Smith, G, Bounds, R, Wolf, H, Steele, RJ, Carey, FA, Wolf, CR

Br. J. Cancer 2010
External Reference Information
External Reference
Gene Names
KRAS, KRAS2, RASK2
Chain
initiator methionine:1, chain:1-186, chain:2-186, propeptide:187-189
Other Identifiers
0006110070
0007040129
11717962_x_at
11717963_a_at
11717964_a_at
11717965_s_at
16762399
1940_at
204009_s_at
204010_s_at
214352_s_at
231640_at
32159_at
3447860
3447862
3447864
3447865
3447866
3447867
3447868
3447869
3447870
3447871
3447872
3447873
3447874
3447879
3447880
3447884
3447886
3845
3958621
7961865
A_23_P306500
A_23_P306507
A_23_P45140
A_33_P3317815
GE61031
GO:0000003
GO:0000165
GO:0000166
GO:0001889
GO:0001934
GO:0002223
GO:0002376
GO:0003674
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005622
GO:0005737
GO:0005739
GO:0005829
GO:0005886
GO:0005925
GO:0006464
GO:0006950
GO:0007010
GO:0007165
GO:0007265
GO:0007267
GO:0007565
GO:0007568
GO:0008150
GO:0008219
GO:0008283
GO:0008284
GO:0008542
GO:0009058
GO:0010628
GO:0016020
GO:0016787
GO:0019002
GO:0019003
GO:0019221
GO:0021897
GO:0030036
GO:0030154
GO:0030275
GO:0031234
GO:0031647
GO:0032228
GO:0034641
GO:0035022
GO:0035900
GO:0038002
GO:0042592
GO:0043167
GO:0043226
GO:0043406
GO:0043524
GO:0044877
GO:0045121
GO:0045596
GO:0048169
GO:0048856
GO:0048873
GO:0050877
GO:0051000
GO:0051092
GO:0051146
GO:0051384
GO:0051385
GO:0060441
GO:2000774
Hs.184050.0.S1_3p_a_at
Hs.184050.1.A1_3p_a_at
Hs.184050.4.A1_3p_at
ILMN_1652104
ILMN_1728071
M54968_at
PH_hs_0028364
PH_hs_0030345
TC12001314.hg
g4826811_3p_a_at
Participant Of
Other forms of this molecule
Modified Residues
Name
L-lysine 117 replaced with L-asparagine
Coordinate
117
PsiMod
A protein modification that effectively removes or replaces an L-lysine.
A protein modification that effectively converts a source amino acid residue to an L-asparagine.
Disease
Name Identifier Synonyms
hematologic cancer 2531 hematopoietic cancer, hematopoietic tumors, Hematologic neoplasm (disorder), Hematologic malignancy, hematopoietic neoplasm (morphologic abnormality), Hematologic malignancy (disorder), Hematological tumors, blood cancer, hematopoietic and lymphoid system tumor, malignant hematopoietic neoplasm (morphologic abnormality)
colorectal cancer 9256
Interactors (2)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04049 RAF1  54 0.623 5
 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate [ChEBI:16618]  6 0.462 2
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