Reactome | C5AR2 binds anaphylatoxins and thier desArginated derivatives

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C5AR2 binds anaphylatoxins and thier desArginated derivatives Show undefined attributes

authored	[InstanceEdit:947693] Jupe, S, 2010-09-10
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:964779] Jupe, S, 2010-09-17
dbId	964811
displayName	C5AR2 binds anaphylatoxins and thier desArginated derivatives
edited	[InstanceEdit:947693] Jupe, S, 2010-09-10
eventOf	[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens [Pathway:R-HSA-977606] Regulation of Complement cascade - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-964798] C5AR2 [plasma membrane] [CandidateSet:R-HSA-964782] C5AR2 ligands [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:964794] The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) [LiteratureReference:964797] The chemoattractant receptor-like protein C5L2 binds the C3a des-Arg77/acylation-stimulating protein
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	C5AR2 binds anaphylatoxins and thier desArginated derivatives
orthologousEvent	[Reaction:R-XTR-964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - Xenopus tropicalis [Reaction:R-DRE-964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - Danio rerio [Reaction:R-SSC-964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - Sus scrofa [Reaction:R-BTA-964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - Bos taurus [Reaction:R-CFA-964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - Canis familiaris [Reaction:R-RNO-964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - Rattus norvegicus [Reaction:R-MMU-964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - Mus musculus
output	[Complex:R-HSA-964812] C5AR2:C5AR2 ligands [plasma membrane]
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:975579] Jassal, B, 2010-10-01
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-964811
summation	[Summation:964791] C5AR2 (GPR77, C5L2) has been described as a receptor for the...
updateTrackers	[UpdateTracker:9783426] Update Tracker - [Reaction:964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - v56:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9783426] Update Tracker - [Reaction:964811] C5AR2 binds anaphylatoxins and thier desArginated derivatives - v56:[modifyText]
(hasEvent)	[Pathway:R-HSA-375276] Peptide ligand-binding receptors [Pathway:R-HSA-977606] Regulation of Complement cascade