Reactome | SapM binds RAB7A

Schema > Reaction > Entries

authored	[InstanceEdit:9635702] Stephan, Ralf, 2019-02-06
category	binding
compartment	[Compartment:70101] cytosol [Compartment:1222693] phagocytic vesicle membrane
created	[InstanceEdit:9636562] Pardo, Agustin, 2019-02-13
crossReference	[DatabaseIdentifier:12020769] Mondo:0018076
dbId	9636564
disease	[Disease:1660556] tuberculosis
displayName	SapM binds RAB7A
edited	[InstanceEdit:9636562] Pardo, Agustin, 2019-02-13
eventOf	[Pathway:R-HSA-9636569] Suppression of autophagy - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9636586] RAB7A [phagocytic vesicle membrane] [EntityWithAccessionedSequence:R-MTU-9636369] SapM [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9636581] Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SapM binds RAB7A
output	[Complex:R-HSA-9636582] SapM:RAB7 [phagocytic vesicle membrane]
precedingEvent	[BlackBoxEvent:R-HSA-9636375] SecA2 transports SapM from cytoplasm to cytosol - Homo sapiens
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2019-12-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9664478] Deffur, Armin, Wilkinson, RJ, 2019-10-23
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9636564
summation	[Summation:9636572] Mtb phosphatidylinositol-3-phosphatase (SapM) blocks autopha...

(hasEvent)

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