Reactome | p16INK4A LoF mutants (CDK4) [cytosol]

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p16INK4A LoF mutants (CDK4) [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-9630792] p16INK4A mutants do not bind CDK4 - Homo sapiens
created	[InstanceEdit:9630825] Orlic-Milacic, Marija, 2018-12-03
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9630826
disease	[Disease:1500689] cancer
displayName	p16INK4A LoF mutants (CDK4) [cytosol]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-9631163] p16INK4A G23S [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631157] p16INK4A G23V [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631314] p16INK4A G35E [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631316] p16INK4A G35R [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631328] p16INK4A G35W [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632206] p16INK4A A60S [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632202] p16INK4A A60E [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632256] p16INK4A T77S [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632523] p16INK4A L97P [cytosol] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-9630828] p16INK4A R24P [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9630892] p16INK4A G23D [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631306] p16INK4A G35A [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631308] p16INK4A G35V [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632088] p16INK4A D74Y [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632192] p16INK4A T18_A19dup [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632212] p16INK4A A60V [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632216] p16INK4A A60R [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632252] p16INK4A G67_N71del [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632257] p16INK4A T77P [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632270] p16INK4A R80P [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632512] p16INK4A L97R [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632531] p16INK4A R99P [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632548] p16INK4A E88K [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632566] p16INK4A R112dup [cytosol] - Homo sapiens
inDisease	true
maxDepth	2
modified	[InstanceEdit:9645190] Orlic-Milacic, Marija, 2019-05-06
name	p16INK4A LoF mutants (CDK4)
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9630826

Referrals

(input)	[FailedReaction:R-HSA-9630792] p16INK4A mutants do not bind CDK4
(diseaseEntity)	[EntityFunctionalStatus:9630827] loss_of_function of p16INK4A LoF mutants (CDK4) [cytosol]

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