Reactome | p-SHC1 binds integrin alpha5beta1:fibronectin

Schema > Reaction > Entries

p-SHC1 binds integrin alpha5beta1:fibronectin Show undefined attributes

authored	[InstanceEdit:9632125] Rothfels, Karen, 2018-12-14
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9624018] Rothfels, Karen, 2018-10-05
dbId	9624017
displayName	p-SHC1 binds integrin alpha5beta1:fibronectin
edited	[InstanceEdit:9758183] Rothfels, Karen, 2021-11-09
eventOf	[Pathway:R-HSA-9634597] GPER1 signaling - Homo sapiens
input	[Complex:R-HSA-2327790] Integrin alpha5beta1:Fibronectin matrix [plasma membrane] [CandidateSet:R-HSA-9623990] pY-SHC1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9623941] Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30 [LiteratureReference:9624251] Fibronectin fibrils and growth factors stimulate anchorage-independent growth of a murine mammary carcinoma [LiteratureReference:9624211] Cooperative effect of hepatocyte growth factor and fibronectin in anchorage-independent survival of mammary carcinoma cells: requirement for phosphatidylinositol 3-kinase activity [LiteratureReference:9624262] The G-protein-coupled estrogen receptor GPER in health and disease
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	p-SHC1 binds integrin alpha5beta1:fibronectin
orthologousEvent	[Reaction:R-BTA-9624017] p-SHC1 binds integrin alpha5beta1:fibronectin - Bos taurus [Reaction:R-GGA-9624017] p-SHC1 binds integrin alpha5beta1:fibronectin - Gallus gallus [Reaction:R-SSC-9624017] p-SHC1 binds integrin alpha5beta1:fibronectin - Sus scrofa [Reaction:R-CFA-9624017] p-SHC1 binds integrin alpha5beta1:fibronectin - Canis familiaris [Reaction:R-RNO-9624017] p-SHC1 binds integrin alpha5beta1:fibronectin - Rattus norvegicus [Reaction:R-MMU-9624017] p-SHC1 binds integrin alpha5beta1:fibronectin - Mus musculus
output	[Complex:R-HSA-9623993] integrin alpha5beta1:Fibronectin matrix:pY-SHC1 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-9624014] SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 - Homo sapiens
releaseDate	2021-12-08
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9645002] Marino, Maria, 2019-04-24 [InstanceEdit:9645003] Acconcia, Filippo, 2019-04-24
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9624017
summation	[Summation:9624007] Estradiol treatment of human breast cancer cells stimulates ...

Referrals

(hasEvent)

[Pathway:R-HSA-9634597] GPER1 signaling