Reactome | SCD5 gene expression

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SCD5 gene expression Show undefined attributes

authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9621401] Rothfels, Karen, 2018-09-26
dbId	9621399
displayName	SCD5 gene expression
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
eventOf	[Pathway:R-HSA-9619665] EGR2 and SOX10-mediated initiation of Schwann cell myelination - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9621342] SCD5 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8847582] Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates [LiteratureReference:8847578] Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells [LiteratureReference:9621609] Transcriptional activation of the stearoyl-CoA desaturase 2 gene by sterol regulatory element-binding protein/adipocyte determination and differentiation factor 1 [LiteratureReference:1655604] Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2 [LiteratureReference:9621573] Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes [LiteratureReference:9613434] Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination [LiteratureReference:9621579] Locus-wide identification of Egr2/Krox20 regulatory targets in myelin genes
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SCD5 gene expression
output	[EntityWithAccessionedSequence:R-HSA-8847580] SCD5 [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-9621400] EGR2 and SREBF2 dimer bind SCD5 gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9621374] Positive gene expression regulation by 'SCD5 gene:EGR2:SREBF2 dimer [nucleoplasm]'
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9621399
summation	[Summation:9621611] Stearoyl-CoA desaturase 5 (SCD5, also known as acyl-CoA desa...

Referrals

(hasEvent)

[Pathway:R-HSA-9619665] EGR2 and SOX10-mediated initiation of Schwann cell myelination