Reactome | EGR1 binds TRIB1 gene

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EGR1 binds TRIB1 gene Show undefined attributes

authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9621387] Rothfels, Karen, 2018-09-26
dbId	9621385
displayName	EGR1 binds TRIB1 gene
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
eventOf	[Pathway:R-HSA-9031628] NGF-stimulated transcription - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9621386] TRIB1 gene expression - Homo sapiens
inferredFrom	[Reaction:R-RNO-9621388] Egr1 binds the Trib1 gene - Rattus norvegicus
input	[EntityWithAccessionedSequence:R-HSA-1031703] EGR1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8960564] TRIB1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9610764] Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells [LiteratureReference:9031578] Global expression analysis identified a preferentially nerve growth factor-induced transcriptional program regulated by sustained mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) and AP-1 protein activation during PC12 cell differentiation
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EGR1 binds TRIB1 gene
output	[Complex:R-HSA-9621362] TRIB1 gene:EGR1 [nucleoplasm]
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9621385
summation	[Summation:9621384] Based on ChIP studies done in rat PC12 cells, EGR1 binds to ...

Referrals

(hasEvent)	[Pathway:R-HSA-9031628] NGF-stimulated transcription
(precedingEvent)	[BlackBoxEvent:R-HSA-9621386] TRIB1 gene expression
(inferredTo)	[Reaction:R-RNO-9621388] Egr1 binds the Trib1 gene

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