Reactome | TPH1 gene expression

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TPH1 gene expression Show undefined attributes

authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9621047] Rothfels, Karen, 2018-09-25
dbId	9621048
displayName	TPH1 gene expression
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
eventOf	[Pathway:R-HSA-9031628] NGF-stimulated transcription - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9620702] TPH1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:976258] Synthesis of serotonin by a second tryptophan hydroxylase isoform [LiteratureReference:9620956] Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function [LiteratureReference:9620983] Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels [LiteratureReference:9620966] Identification of a functional TPH1 polymorphism associated with irritable bowel syndrome bowel habit subtypes [LiteratureReference:9031578] Global expression analysis identified a preferentially nerve growth factor-induced transcriptional program regulated by sustained mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) and AP-1 protein activation during PC12 cell differentiation [LiteratureReference:9610764] Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TPH1 gene expression
output	[EntityWithAccessionedSequence:R-HSA-976250] TPH1 [cytosol]
precedingEvent	[Reaction:R-HSA-9621032] EGR1 binds the TPH1 promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9621049] Positive gene expression regulation by 'TPH1 gene:EGR1 [nucleoplasm]'
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9621048
summation	[Summation:9621045] TPH1 (Tryptophan hydroxylase 1) is one of two tryptophan hyd...

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(hasEvent)

[Pathway:R-HSA-9031628] NGF-stimulated transcription