Reactome | EGR1 binds the TF gene

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EGR1 binds the TF gene Show undefined attributes

authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9621037] Rothfels, Karen, 2018-09-25
dbId	9621035
displayName	EGR1 binds the TF gene
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
eventOf	[Pathway:R-HSA-9031628] NGF-stimulated transcription - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9621042] TF gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-1031703] EGR1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8960687] TF gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9620711] Transcriptional regulation of the tissue factor gene in human epithelial cells is mediated by Sp1 and EGR-1 [LiteratureReference:9031578] Global expression analysis identified a preferentially nerve growth factor-induced transcriptional program regulated by sustained mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) and AP-1 protein activation during PC12 cell differentiation [LiteratureReference:9610764] Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells [LiteratureReference:9621016] How it all starts: Initiation of the clotting cascade
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EGR1 binds the TF gene
output	[Complex:R-HSA-9621038] TF gene:EGR1 [nucleoplasm]
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9621035
summation	[Summation:9621036] EGR1 binds to the promoter of the TF gene to induce transcri...

Referrals

(hasEvent)	[Pathway:R-HSA-9031628] NGF-stimulated transcription
(precedingEvent)	[BlackBoxEvent:R-HSA-9621042] TF gene expression