Reactome | p-S516-ARHGEF7 activates RAC1

Schema > Reaction > Entries

authored	[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
catalystActivity	[CatalystActivity:9619805] guanyl-nucleotide exchange factor activity of GIT1:p-S516-ARHGEF7-1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9619802] Orlic-Milacic, Marija, 2018-09-18
dbId	9619803
displayName	p-S516-ARHGEF7 activates RAC1
edited	[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
eventOf	[Pathway:R-HSA-9619229] Activation of RAC1 downstream of NMDARs - Homo sapiens
inferredFrom	[Reaction:R-RNO-9619811] p-S516-Arhgef7 activates Rac1 - Rattus norvegicus
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-HSA-5674631] RAC1:GDP [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-S516-ARHGEF7 activates RAC1
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-HSA-442641] RAC1:GTP [plasma membrane]
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9619803
summation	[Summation:9619804] CAMK1-mediated phosphorylation of ARHGEF7 (Beta-Pix) at seri...

(hasEvent)	[Pathway:R-HSA-9619229] Activation of RAC1 downstream of NMDARs
(inferredTo)	[Reaction:R-RNO-9619811] p-S516-Arhgef7 activates Rac1

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