Reactome | ADGRG heterodimer translocates to plasma membrane

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ADGRG heterodimer translocates to plasma membrane Show undefined attributes

authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
category	omitted
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9614272] Rothfels, Karen, 2018-07-24
dbId	9614273
displayName	ADGRG heterodimer translocates to plasma membrane
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
eventOf	[Pathway:R-HSA-9619665] EGR2 and SOX10-mediated initiation of Schwann cell myelination - Homo sapiens
input	[Complex:R-HSA-9614270] ADGRG6-CTF:ADGRG6-NTF [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9614599] DREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sites [LiteratureReference:9614589] A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis [LiteratureReference:9614621] Sticky signaling--adhesion class G protein-coupled receptors take the stage [LiteratureReference:9614591] Adhesion G-protein coupled receptors and extracellular matrix proteins: Roles in myelination and glial cell development
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	ADGRG heterodimer translocates to plasma membrane
orthologousEvent	[BlackBoxEvent:R-DRE-9614273] ADGRG heterodimer translocates to plasma membrane - Danio rerio [BlackBoxEvent:R-CEL-9614273] ADGRG heterodimer translocates to plasma membrane - Caenorhabditis elegans [BlackBoxEvent:R-DME-9614273] ADGRG heterodimer translocates to plasma membrane - Drosophila melanogaster [BlackBoxEvent:R-GGA-9614273] ADGRG heterodimer translocates to plasma membrane - Gallus gallus [BlackBoxEvent:R-SSC-9614273] ADGRG heterodimer translocates to plasma membrane - Sus scrofa [BlackBoxEvent:R-BTA-9614273] ADGRG heterodimer translocates to plasma membrane - Bos taurus [BlackBoxEvent:R-CFA-9614273] ADGRG heterodimer translocates to plasma membrane - Canis familiaris [BlackBoxEvent:R-RNO-9614273] ADGRG heterodimer translocates to plasma membrane - Rattus norvegicus [BlackBoxEvent:R-MMU-9614273] ADGRG heterodimer translocates to plasma membrane - Mus musculus
output	[Complex:R-HSA-9614274] ADGRG6-CTF:ADGRG6-NTF [plasma membrane]
precedingEvent	[Reaction:R-HSA-9614271] Autocleavage of ADGRG6 - Homo sapiens
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9614273
summation	[Summation:9614636] Mature ADGRG6 is expressed at the plasma membrane as a non-c...

Referrals

(hasEvent)

[Pathway:R-HSA-9619665] EGR2 and SOX10-mediated initiation of Schwann cell myelination