Reactome | Expression of PLIN1 regulated by NR1H2 or NR1H3

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
category	uncertain
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9608047] Shamovsky, Veronica, 2018-05-08
dbId	9608048
displayName	Expression of PLIN1 regulated by NR1H2 or NR1H3
edited	[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
eventOf	[Pathway:R-HSA-9031528] NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-5640178] PLIN1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9608024] Liver X receptor (LXR) regulates human adipocyte lipolysis
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of PLIN1 regulated by NR1H2 or NR1H3
output	[EntityWithAccessionedSequence:R-HSA-163460] PLIN1 [lipid droplet]
precedingEvent	[Reaction:R-HSA-9608039] NR1H2,3 binds the PLIN1 gene - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:9608050] 'PLIN1 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm]' negatively regulates 'Expression of PLIN1 regulated by NR1H2,3'
releaseDate	2019-09-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29 [InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9608048
summation	[Summation:9608049] The perilipin 1 (PLIN1) gene is transcribed to yield mRNA an...

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