Reactome | B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain

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B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain Show undefined attributes

authored	[InstanceEdit:9603988] Jassal, Bijay, 2018-03-29
catalystActivity	[CatalystActivity:913721] N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity of B3GALTs [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:9603988] Jassal, Bijay, 2018-03-29
dbId	9603989
displayName	B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain
edited	[InstanceEdit:9603988] Jassal, Bijay, 2018-03-29
eventOf	[Pathway:R-HSA-9037629] Lewis blood group biosynthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-9603986] FUT3 transfers Fuc to Type 1 chains to form LeA - Homo sapiens [Reaction:R-HSA-9603987] ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG - Homo sapiens
input	[SimpleEntity:R-ALL-9604808] GlcNAc-?1,3-Gal-R [Golgi lumen] [SimpleEntity:R-ALL-735682] UDP-Gal [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:977007] A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family [LiteratureReference:9604801] Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom [LiteratureReference:9604799] The galactosyltransferase family
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain
orthologousEvent	[Reaction:R-BTA-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Bos taurus [Reaction:R-CEL-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Caenorhabditis elegans [Reaction:R-DME-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Drosophila melanogaster [Reaction:R-GGA-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Gallus gallus [Reaction:R-XTR-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Xenopus tropicalis [Reaction:R-DRE-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Danio rerio [Reaction:R-SSC-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Sus scrofa [Reaction:R-CFA-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Canis familiaris [Reaction:R-RNO-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Rattus norvegicus [Reaction:R-MMU-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Mus musculus
output	[SimpleEntity:R-ALL-9036984] Type 1 chain [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
releaseDate	2019-03-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9632249] Matsui, Taei, 2018-12-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9603989
summation	[Summation:9604804] The family of beta-1,3-galactosyltransferases (B3GALTs) tran...

Referrals

(hasEvent)	[Pathway:R-HSA-9037629] Lewis blood group biosynthesis
(precedingEvent)	[Reaction:R-HSA-9603986] FUT3 transfers Fuc to Type 1 chains to form LeA [Reaction:R-HSA-9603987] ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG

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