The family of beta-1,3-galactosyltransferases (B3GALTs) tran...

created [InstanceEdit:9604805] Jassal, Bijay, 2018-04-05
dbId 9604804
displayName The family of beta-1,3-galactosyltransferases (B3GALTs) tran...
modified [InstanceEdit:9610580] Jassal, Bijay, 2018-06-11
schemaClass Summation
text The family of beta-1,3-galactosyltransferases (B3GALTs) transfer galactose (Gal) from UDP-alpha-D-galactose (UDP-Gal) to the ?1,3 position of substrates with a terminal beta-N-acetylglucosamine (?-GlcNAc) residue. B3GALTs are involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Here, five members of this family (B3GALT1-5) can mediate the transfer of Gal to GlcNAc-?1,3-Gal-R, the precursor to blood group Type 1 oligosaccharide chains found in bodily secretions (Amado et al. 1998, Isshiki et al. 1999; review Hennet 2002).
Cite Us!