Reactome | FUT2 transfers Fuc to LeX to form LeY

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FUT2 transfers Fuc to LeX to form LeY Show undefined attributes

authored	[InstanceEdit:9603988] Jassal, Bijay, 2018-03-29
catalystActivity	[CatalystActivity:9036986] galactoside 2-alpha-L-fucosyltransferase activity of FUT2 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:9603988] Jassal, Bijay, 2018-03-29
dbId	9603983
displayName	FUT2 transfers Fuc to LeX to form LeY
edited	[InstanceEdit:9603988] Jassal, Bijay, 2018-03-29
eventOf	[Pathway:R-HSA-9037629] Lewis blood group biosynthesis - Homo sapiens
input	[SimpleEntity:R-ALL-205683] GDP-Fuc [Golgi lumen] [SimpleEntity:R-ALL-9605593] LeX [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9034035] Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype [LiteratureReference:9034048] Structure and expression of the gene encoding secretor-type galactoside 2-alpha-L-fucosyltransferase (FUT2)
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	FUT2 transfers Fuc to LeX to form LeY
orthologousEvent	[Reaction:R-BTA-9603983] FUT2 transfers Fuc to LeX to form LeY - Bos taurus [Reaction:R-CEL-9603983] FUT2 transfers Fuc to LeX to form LeY - Caenorhabditis elegans [Reaction:R-XTR-9603983] FUT2 transfers Fuc to LeX to form LeY - Xenopus tropicalis [Reaction:R-SSC-9603983] FUT2 transfers Fuc to LeX to form LeY - Sus scrofa [Reaction:R-CFA-9603983] FUT2 transfers Fuc to LeX to form LeY - Canis familiaris [Reaction:R-RNO-9603983] FUT2 transfers Fuc to LeX to form LeY - Rattus norvegicus [Reaction:R-MMU-9603983] FUT2 transfers Fuc to LeX to form LeY - Mus musculus
output	[SimpleEntity:R-ALL-205689] GDP [Golgi lumen] [SimpleEntity:R-ALL-9605586] LeY [Golgi lumen]
precedingEvent	[Reaction:R-HSA-9033949] FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC - Homo sapiens
releaseDate	2019-03-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9632249] Matsui, Taei, 2018-12-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9603983
summation	[Summation:9605628] The FUT2 gene (originally named the Se gene) e...

Referrals

(hasEvent)

[Pathway:R-HSA-9037629] Lewis blood group biosynthesis