Reactome | UPF1 [cytosol]

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UPF1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-927762] UPF1:eRF3 Complex on Translated mRNA [cytosol] - Homo sapiens [Complex:R-HSA-927767] SMG1:UPF1:EJC:Translated mRNP [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-927789] Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex - Homo sapiens [Reaction:R-HSA-927832] UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex - Homo sapiens
created	[InstanceEdit:927892] May, B, 2010-08-10
dbId	927734
displayName	UPF1 [cytosol]
endCoordinate	1129
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-927734] UPF1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-927734] Upf1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-927734] UPF1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-927734] UPF1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-927734] UPF1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-927734] UPF1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-927734] upf1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-927734] UPF1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-927734] UPF1 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-927734] UPF1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-927734] UPF1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-927734] UPF1 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-927734] UPF1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-927734] UPF1 [cytosol] - Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	UPF1 Regulator of nonsense transcripts 1 RENT1_HUMAN
producedByEvent	[BlackBoxEvent:R-HSA-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q92900] UniProt:Q92900 UPF1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-927734
startCoordinate	1

Referrals

(output)	[BlackBoxEvent:R-HSA-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex
(input)	[Reaction:R-HSA-927832] UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex [Reaction:R-HSA-927789] Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex
(hasComponent)	[Complex:R-HSA-927767] SMG1:UPF1:EJC:Translated mRNP [cytosol] [Complex:R-HSA-927762] UPF1:eRF3 Complex on Translated mRNA [cytosol]

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