Reactome | GCNT3 transfers GlcNAc to Core 3 mucin

Schema > Reaction > Entries

GCNT3 transfers GlcNAc to Core 3 mucin Show undefined attributes

authored	[InstanceEdit:913626] Jassal, B, 2010-07-19
catalystActivity	[CatalystActivity:976831] beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity of GCNT3 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:914014] Jassal, B, 2010-07-21
crossReference	[DatabaseIdentifier:9942403] RHEA:56189 [DatabaseIdentifier:9942399] RHEA:56193
dbId	914018
displayName	GCNT3 transfers GlcNAc to Core 3 mucin
edited	[InstanceEdit:913626] Jassal, B, 2010-07-19
eventOf	[Pathway:R-HSA-913709] O-linked glycosylation of mucins - Homo sapiens
input	[DefinedSet:R-HSA-1462159] Core 3 mucins [Golgi lumen] [SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:977025] Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches [LiteratureReference:977072] Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	GCNT3 transfers GlcNAc to Core 3 mucin Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein
orthologousEvent	[Reaction:R-GGA-914018] GCNT3 transfers GlcNAc to Core 3 mucin - Gallus gallus [Reaction:R-DRE-914018] GCNT3 transfers GlcNAc to Core 3 mucin - Danio rerio [Reaction:R-SSC-914018] GCNT3 transfers GlcNAc to Core 3 mucin - Sus scrofa [Reaction:R-BTA-914018] GCNT3 transfers GlcNAc to Core 3 mucin - Bos taurus [Reaction:R-CFA-914018] GCNT3 transfers GlcNAc to Core 3 mucin - Canis familiaris [Reaction:R-RNO-914018] GCNT3 transfers GlcNAc to Core 3 mucin - Rattus norvegicus [Reaction:R-MMU-914018] GCNT3 transfers GlcNAc to Core 3 mucin - Mus musculus
output	[DefinedSet:R-HSA-1462144] Core 4 mucins [Golgi lumen] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
precedingEvent	[Reaction:R-HSA-914010] B3GNT6 transfers GlcNAc to Tn antigen - Homo sapiens
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1964508] Ferrer, A, 2011-11-04 [InstanceEdit:9944933] D'Eustachio, Peter, 2025-04-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-914018
summation	[Summation:977076] The glycosyltransferase GCNT3 mediates core 2 and core 4 O-g...
updateTrackers	[UpdateTracker:9953725] Update Tracker - [Reaction:914018] GCNT3 transfers GlcNAc to Core 3 mucin - v93:[removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9953725] Update Tracker - [Reaction:914018] GCNT3 transfers GlcNAc to Core 3 mucin - v93:[removeOutput]
(hasEvent)	[Pathway:R-HSA-913709] O-linked glycosylation of mucins

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