Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein

Stable Identifier
R-HSA-914018
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The glycosyltransferase GCNT3 mediates core 2 and core 4 O-glycan branching (Yeh et al, 1999; Schwientek et al, 1999).

Literature References
PubMed ID Title Journal Year
9988682 Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4

Schwientek, T, Nomoto, M, Levery, SB, Merkx, G, van Kessel, AG, Bennett, EP, Hollingsworth, MA, Clausen, H

J Biol Chem 1999
9915862 Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches

Yeh, JC, Ong, E, Fukuda, M

J Biol Chem 1999
Participants
Participates
Catalyst Activity

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity of GCNT3 [Golgi membrane]

Orthologous Events
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