Reactome | GCNT3 transfers GlcNAc to Core 3 mucin

GCNT3 transfers GlcNAc to Core 3 mucin

Stable Identifier

R-HSA-914018

Type

Reaction [transition]

Species

Homo sapiens

Compartment

Golgi membrane, Golgi lumen

Synonyms

Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein

ReviewStatus

5/5

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The glycosyltransferase GCNT3 mediates core 2 and core 4 O-glycan branching (Yeh et al, 1999; Schwientek et al, 1999).

Literature References

PubMed ID	Title	Journal	Year
9915862	Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches Yeh, JC, Ong, E, Fukuda, M	J Biol Chem	1999
9988682	Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4 Schwientek, T, Nomoto, M, Levery, SB, Merkx, G, van Kessel, AG, Bennett, EP, Hollingsworth, MA, Clausen, H	J Biol Chem	1999