Reactome | IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]

Schema > Complex > Entries

IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:909717] protein tyrosine kinase activity of IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-912680] Inhibition of JAK kinase activity by SOCS1/3 - Homo sapiens [Reaction:R-HSA-909729] Activation of JAK kinases - Homo sapiens
created	[InstanceEdit:909716] Garapati, P V, 2010-07-07
dbId	909703
displayName	IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]
hasComponent	[Complex:R-HSA-918195] IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] [Complex:R-HSA-909708] IFNAR1:TYK2 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - Mus musculus [Complex:R-RNO-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - Canis familiaris [Complex:R-BTA-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - Bos taurus [Complex:R-SSC-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - Sus scrofa [Complex:R-DRE-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - Danio rerio [Complex:R-GGA-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - Gallus gallus
isChimeric	false
maxDepth	5
modified	[InstanceEdit:918289] Garapati, P V, 2010-08-03
name	IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2
producedByEvent	[Reaction:R-HSA-997314] Dephosphorylation of JAK1 by SHP1 - Homo sapiens [Reaction:R-HSA-909724] Recruitment of IFNAR1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-909703
updateTrackers	[UpdateTracker:9984777] Update Tracker - [Complex:909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - v96:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9984777] Update Tracker - [Complex:909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - v96:[updateContainedComponent]
(input)	[Reaction:R-HSA-912680] Inhibition of JAK kinase activity by SOCS1/3 [Reaction:R-HSA-909729] Activation of JAK kinases
(output)	[Reaction:R-HSA-997314] Dephosphorylation of JAK1 by SHP1 [Reaction:R-HSA-909724] Recruitment of IFNAR1
(physicalEntity)	[CatalystActivity:909717] protein tyrosine kinase activity of IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]

© 2026 Reactome

Cite Us!