Reactome | IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10261304] protein tyrosine kinase activity of IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-CFA-909729] Activation of JAK kinases - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10261294
displayName	IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]
hasComponent	[Complex:R-CFA-918195] IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] [Complex:R-CFA-909708] IFNAR1:TYK2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] - Homo sapiens
maxDepth	6
name	IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2
producedByEvent	[Reaction:R-CFA-997314] Dephosphorylation of JAK1 by SHP1 - Canis familiaris [Reaction:R-CFA-909724] Recruitment of IFNAR1 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-909703
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-CFA-997314] Dephosphorylation of JAK1 by SHP1 [Reaction:R-CFA-909724] Recruitment of IFNAR1
(input)	[Reaction:R-CFA-909729] Activation of JAK kinases
(physicalEntity)	[CatalystActivity:10261304] protein tyrosine kinase activity of IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]
(inferredTo)	[Complex:R-HSA-909703] IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]

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