Reactome | miR-613 binds to the 3'UTR of the NR1H3 mRNA

Schema > Reaction > Entries

authored	[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9038542] Shamovsky, Veronica, 2018-03-06
dbId	9038545
displayName	miR-613 binds to the 3'UTR of the NR1H3 mRNA
edited	[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
eventOf	[Pathway:R-HSA-9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux - Homo sapiens
input	[DefinedSet:R-HSA-9038541] miR-613 RISC [cytosol] [EntityWithAccessionedSequence:R-HSA-9038553] NR1H3 mRNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9038551] MicroRNA-613 represses lipogenesis in HepG2 cells by downregulating LXR? [LiteratureReference:9038557] MicroRNA hsa-miR-613 targets the human LXR? gene and mediates a feedback loop of LXR? autoregulation
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	miR-613 binds to the 3'UTR of the NR1H3 mRNA
output	[Complex:R-HSA-9038554] NR1H3 mRNA:miR-613 RISC [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-9035281] NR1H3 gene transcription regulated by NR1H2,3 - Homo sapiens
releaseDate	2019-09-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29 [InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9038545
summation	[Summation:9038535] Translation of liver X receptor ? (LXR? or NR1H3) mRNA is ne...

(hasEvent)

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