Reactome | NTF4 binds NTRK2

Schema > Reaction > Entries

authored	[InstanceEdit:9034391] Orlic-Milacic, Marija, 2018-01-05
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9026359] Orlic-Milacic, Marija, 2017-10-19
dbId	9026358
displayName	NTF4 binds NTRK2
edited	[InstanceEdit:9037703] Orlic-Milacic, Marija, 2018-02-20
eventOf	[Pathway:R-HSA-9026357] NTF4 activates NTRK2 (TRKB) signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-9026377] NTF4-bound NTRK2 dimerizes - Homo sapiens
inferredFrom	[Reaction:R-NUL-9026445] ntf4 binds Ntrk2 - Xenopus laevis
input	[Complex:R-HSA-9025082] NTF4 homodimer [extracellular region] [EntityWithAccessionedSequence:R-HSA-6798236] NTRK2 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NTF4 binds NTRK2
output	[Complex:R-HSA-9026356] NTF4:NTRK2 [plasma membrane]
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9037707] Antila, Hanna, 2018-02-13 [InstanceEdit:9037710] Castr�n, Eero, 2018-02-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9026358
summation	[Summation:9026444] The neurotrophic factor NTF4 (neurotrophin-4), which functio...

(hasEvent)	[Pathway:R-HSA-9026357] NTF4 activates NTRK2 (TRKB) signaling
(precedingEvent)	[Reaction:R-HSA-9026377] NTF4-bound NTRK2 dimerizes
(inferredTo)	[Reaction:R-NUL-9026445] ntf4 binds Ntrk2

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