Reactome | RHOT2 binds effectors at the mitochondrial outer membrane

Schema > Reaction > Entries

RHOT2 binds effectors at the mitochondrial outer membrane Show undefined attributes

authored	[InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
category	binding
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:9018828] Orlic-Milacic, Marija, 2017-09-05
dbId	9018824
deleted	[Deleted:9716816] Deletion of instance: 194894
displayName	RHOT2 binds effectors at the mitochondrial outer membrane
edited	[InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
eventOf	[Pathway:R-HSA-9013419] RHOT2 GTPase cycle - Homo sapiens
input	[DefinedSet:R-HSA-9020433] RHOT2 effectors [cytosol] [Complex:R-HSA-9020438] RHOT2:GTP [mitochondrial outer membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9693816] The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking [LiteratureReference:9693834] MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca²⁺ Stress [LiteratureReference:9693847] Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX [LiteratureReference:9693859] The MyMOMA domain of MYO19 encodes for distinct Miro-dependent and Miro-independent mechanisms of interaction with mitochondrial membranes
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	RHOT2 binds effectors at the mitochondrial outer membrane
orthologousEvent	[Reaction:R-SCE-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Saccharomyces cerevisiae [Reaction:R-SPO-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Schizosaccharomyces pombe [Reaction:R-CEL-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Caenorhabditis elegans [Reaction:R-DME-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Drosophila melanogaster [Reaction:R-GGA-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Gallus gallus [Reaction:R-XTR-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Xenopus tropicalis [Reaction:R-DRE-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Danio rerio [Reaction:R-SSC-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Sus scrofa [Reaction:R-BTA-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Bos taurus [Reaction:R-RNO-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Rattus norvegicus [Reaction:R-MMU-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Mus musculus
output	[Complex:R-HSA-9020439] RHOT2:GTP:RHOT2 effectors [mitochondrial outer membrane]
precedingEvent	[Reaction:R-HSA-9018825] RHOT2 GEFs activate RHOT2 - Homo sapiens
releaseDate	2021-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9714635] Schrader, Michael, 2021-02-09 [InstanceEdit:9714634] Castro, In�s G, 2021-02-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9018824
summation	[Summation:9693810] Active GTP-bound RHOT2 interacts with the following effector...

Referrals

(replacementInstances)	[Deleted:9716816] Deletion of instance: 194894
(hasEvent)	[Pathway:R-HSA-9013419] RHOT2 GTPase cycle