Reactome | RHOT2 GTPase cycle

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RHOT2 GTPase cycle Show undefined attributes

authored	[InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
created	[InstanceEdit:9013421] Orlic-Milacic, Marija, 2017-07-24
dbId	9013419
displayName	RHOT2 GTPase cycle
edited	[InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
eventOf	[Pathway:R-HSA-9715370] Miro GTPase Cycle - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-9018825] RHOT2 GEFs activate RHOT2 - Homo sapiens [Reaction:R-HSA-9018826] RHOT2 hydrolyzes GTP - Homo sapiens [Reaction:R-HSA-9018824] RHOT2 binds effectors at the mitochondrial outer membrane - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9693793] Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism [LiteratureReference:9695506] Miro sculpts mitochondrial dynamics in neuronal health and disease [LiteratureReference:9714598] Peroxisomal fission is modulated by the mitochondrial Rho-GTPases, Miro1 and Miro2
maxDepth	2
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	RHOT2 GTPase cycle
orthologousEvent	[Pathway:R-SCE-9013419] RHOT2 GTPase cycle - Saccharomyces cerevisiae [Pathway:R-SPO-9013419] RHOT2 GTPase cycle - Schizosaccharomyces pombe [Pathway:R-CEL-9013419] RHOT2 GTPase cycle - Caenorhabditis elegans [Pathway:R-DME-9013419] RHOT2 GTPase cycle - Drosophila melanogaster [Pathway:R-GGA-9013419] RHOT2 GTPase cycle - Gallus gallus [Pathway:R-XTR-9013419] RHOT2 GTPase cycle - Xenopus tropicalis [Pathway:R-DRE-9013419] RHOT2 GTPase cycle - Danio rerio [Pathway:R-SSC-9013419] RHOT2 GTPase cycle - Sus scrofa [Pathway:R-BTA-9013419] RHOT2 GTPase cycle - Bos taurus [Pathway:R-RNO-9013419] RHOT2 GTPase cycle - Rattus norvegicus [Pathway:R-MMU-9013419] RHOT2 GTPase cycle - Mus musculus
releaseDate	2021-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9714635] Schrader, Michael, 2021-02-09 [InstanceEdit:9714634] Castro, In�s G, 2021-02-09
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9013419
summation	[Summation:9693805] This pathway catalogues guanine nucleotide exchange factors ...

Referrals

(hasEvent)

[Pathway:R-HSA-9715370] Miro GTPase Cycle