Reactome | Estrogen-responsive CXXC5 gene expresion

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Estrogen-responsive CXXC5 gene expresion Show undefined attributes

authored	[InstanceEdit:9024061] Rothfels, Karen, 2017-09-29
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9018333] Rothfels, Karen, 2017-08-30
dbId	9018334
displayName	Estrogen-responsive CXXC5 gene expresion
edited	[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
eventOf	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9018329] CXXC5 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9018300] Estradiol-Estrogen Receptor ? Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway [LiteratureReference:9018306] Genomic responses from the estrogen-responsive element-dependent signaling pathway mediated by estrogen receptor alpha are required to elicit cellular alterations [LiteratureReference:9018297] CXXC5 regulates differentiation of C2C12 myoblasts into myocytes [LiteratureReference:9018246] A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway [LiteratureReference:9018277] CXXC5 plays a role as a transcription activator for myelin genes on oligodendrocyte differentiation [LiteratureReference:9018313] Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2 [LiteratureReference:9018268] CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells [LiteratureReference:9018249] CXXC5 is a negative-feedback regulator of the Wnt/?-catenin pathway involved in osteoblast differentiation [LiteratureReference:9018318] The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing [LiteratureReference:9018232] CXXC5 Associates with Smads to Mediate TNF-? Induced Apoptosis
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Estrogen-responsive CXXC5 gene expresion
output	[EntityWithAccessionedSequence:R-HSA-9018222] CXXC5 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9018325] ESR1:ESTG binds CXXC5 gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-9018340] Positive gene expression regulation by 'CXXC5 gene:ESR1:ESTG [nucleoplasm]' [PositiveRegulation:R-HSA-9020555] Positive regulation by 'KANK1 [nucleoplasm]'
regulationReference	[RegulationReference:9641996] Positive regulation by 'KANK1 [nucleoplasm]' Nucleo-cytoplasmic shuttling of human Kank protein accompanies intracellular translocation of beta-catenin [RegulationReference:9642024] Positive gene expression regulation by 'CXXC5 gene:ESR1:ESTG [nucleoplasm]' Estradiol-Estrogen Receptor ? Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9018334
summation	[Summation:9018233] CXXC5 expression is estrogen-responsive and depends on the i...
updateTrackers	[UpdateTracker:9776278] Update Tracker - [BlackBoxEvent:9018334] Estrogen-responsive CXXC5 gene expresion - v77:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9776278] Update Tracker - [BlackBoxEvent:9018334] Estrogen-responsive CXXC5 gene expresion - v77:[modifyText]
(hasEvent)	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression

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