Reactome | K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane]

Schema > Complex > Entries

K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] Show undefined attributes

compartment	[Compartment:74700] endosome membrane
componentOf	[Complex:R-HSA-9013980] TANK:K63-poly-Ub-TRAF3:TICAM1:viral dsRNA:TLR3 [endosome membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9013985] TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR3 - Homo sapiens
created	[InstanceEdit:9013993] Shamovsky, Veronica, 2017-07-26
dbId	9013989
displayName	K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-HSA-936402] K63polyUb-TRAF3 [cytosol] [Complex:R-HSA-168907] viral dsRNA:TLR3:TICAM1 [endosome membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:171907] endosome lumen
isChimeric	false
literatureReference	[LiteratureReference:433920] Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6 [LiteratureReference:918164] Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
maxDepth	5
modified	[InstanceEdit:9031727] D'Eustachio, Peter, 2017-12-01
name	K63polyUb-TRAF3:TICAM1:activated TLR3 K63polyUb-TRAF3:TRIF:activated TLR3
producedByEvent	[BlackBoxEvent:R-HSA-9013974] Auto-ubiquitination of TRAF3 within activated TLR3 complex - Homo sapiens
relatedSpecies	[Species:5229092] Hepatitis B virus [Species:5621375] Hepatitis C Virus [Species:5689680] Human herpesvirus 1 [Species:5617433] Rotavirus [Species:9031716] Influenza A virus
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9013989
updateTrackers	[UpdateTracker:9898415] Update Tracker - [Complex:9013989] K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] - v63:[updateContainedComponent] [UpdateTracker:9898962] Update Tracker - [Complex:9013989] K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] - v64:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9898415] Update Tracker - [Complex:9013989] K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] - v63:[updateContainedComponent] [UpdateTracker:9898962] Update Tracker - [Complex:9013989] K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] - v64:[updateContainedComponent]
(output)	[BlackBoxEvent:R-HSA-9013974] Auto-ubiquitination of TRAF3 within activated TLR3 complex
(input)	[Reaction:R-HSA-9013985] TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR3
(hasComponent)	[Complex:R-HSA-9013980] TANK:K63-poly-Ub-TRAF3:TICAM1:viral dsRNA:TLR3 [endosome membrane] [Complex:R-HSA-9013976] K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane]