Reactome | RHOC GTPase cycle

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RHOC GTPase cycle Show undefined attributes

authored	[InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
created	[InstanceEdit:9013107] Orlic-Milacic, Marija, 2017-07-23
dbId	9013106
displayName	RHOC GTPase cycle
edited	[InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
eventOf	[Pathway:R-HSA-9012999] RHO GTPase cycle - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-9013109] RHOC GEFs activate RHOC - Homo sapiens [Reaction:R-HSA-9013111] RHOC GAPs stimulate RHOC GTPase activity - Homo sapiens [Reaction:R-HSA-9013108] GDIs block activation of RHOC - Homo sapiens [Reaction:R-HSA-9013110] RHOC binds effectors at the plasma membrane - Homo sapiens [BlackBoxEvent:R-HSA-9714363] RHOC translocates to the endoplasmic reticulum membrane - Homo sapiens [Reaction:R-HSA-9714361] RHOC activates endoplasmic reticulum effectors - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9694179] Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility [LiteratureReference:9694185] The role of RhoC in malignant tumor invasion, metastasis and targeted therapy [LiteratureReference:9694176] Spatial regulation of tumor cell protrusions by RhoC [LiteratureReference:9694190] RhoC: a fascinating journey from a cytoskeletal organizer to a Cancer stem cell therapeutic target
maxDepth	2
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	RHOC GTPase cycle
orthologousEvent	[Pathway:R-SCE-9013106] RHOC GTPase cycle - Saccharomyces cerevisiae [Pathway:R-SPO-9013106] RHOC GTPase cycle - Schizosaccharomyces pombe [Pathway:R-GGA-9013106] RHOC GTPase cycle - Gallus gallus [Pathway:R-XTR-9013106] RHOC GTPase cycle - Xenopus tropicalis [Pathway:R-DRE-9013106] RHOC GTPase cycle - Danio rerio [Pathway:R-SSC-9013106] RHOC GTPase cycle - Sus scrofa [Pathway:R-BTA-9013106] RHOC GTPase cycle - Bos taurus [Pathway:R-CFA-9013106] RHOC GTPase cycle - Canis familiaris [Pathway:R-RNO-9013106] RHOC GTPase cycle - Rattus norvegicus [Pathway:R-MMU-9013106] RHOC GTPase cycle - Mus musculus
releaseDate	2021-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9714226] Fort, Philippe, 2021-02-05
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9013106
summation	[Summation:9694193] This pathway catalogues RHOC guanine nucleotide exchange fac...

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(hasEvent)

[Pathway:R-HSA-9012999] RHO GTPase cycle

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