Reactome | Estrogen-responsive KPNA2 gene transcription

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9024061] Rothfels, Karen, 2017-09-29
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9012211] Rothfels, Karen, 2017-07-11
dbId	9012209
displayName	Estrogen-responsive KPNA2 gene transcription
edited	[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
eventOf	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression - Homo sapiens
followingEvent	[Reaction:R-HSA-9012208] miR-26A and B bind to the 3'UTR of the KPNA2 mRNA - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9012165] KPNA2 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9012200] The functional role of the novel biomarker karyopherin ? 2 (KPNA2) in cancer [LiteratureReference:9012130] Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Estrogen-responsive KPNA2 gene transcription
output	[EntityWithAccessionedSequence:R-HSA-9012169] KPNA2 mRNA [cytosol]
regulatedBy	[PositiveRegulation:R-HSA-9012300] Positive regulation by 'ESTG [nucleoplasm]'
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9012209
summation	[Summation:9012192] KPNA2 is a member of the karyopherin alpha family that recog...

(precedingEvent)	[Reaction:R-HSA-9012208] miR-26A and B bind to the 3'UTR of the KPNA2 mRNA
(hasEvent)	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression

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