Reactome | miR-26A and B bind to the 3'UTR of the KPNA2 mRNA

Schema > Reaction > Entries

authored	[InstanceEdit:9024061] Rothfels, Karen, 2017-09-29
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9012211] Rothfels, Karen, 2017-07-11
dbId	9012208
displayName	miR-26A and B bind to the 3'UTR of the KPNA2 mRNA
edited	[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
eventOf	[Pathway:R-HSA-9018519] Estrogen-dependent gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9012169] KPNA2 mRNA [cytosol] [DefinedSet:R-HSA-9011867] miR-26 RISC [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9012130] Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2 [LiteratureReference:9012147] MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	miR-26A and B bind to the 3'UTR of the KPNA2 mRNA
output	[Complex:R-HSA-9012172] KPNA2 mRNA:mIR-26 RISC [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-9012209] Estrogen-responsive KPNA2 gene transcription - Homo sapiens
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9012208
summation	[Summation:9012210] Translation of KPNA2 mRNA is negatively regulated by mIR-26A...

(hasEvent)

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