Reactome | RUNX2 binds HAND2

Schema > Reaction > Entries

authored	[InstanceEdit:9007814] Orlic-Milacic, Marija, 2017-06-05
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9007814] Orlic-Milacic, Marija, 2017-06-05
dbId	9007816
displayName	RUNX2 binds HAND2
edited	[InstanceEdit:9015332] Orlic-Milacic, Marija, 2017-08-09
eventOf	[Pathway:R-HSA-8878166] Transcriptional regulation by RUNX2 - Homo sapiens
inferredFrom	[Reaction:R-MMU-9007813] Runx2 binds Hand2 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9007820] HAND2 [nucleoplasm] [CandidateSet:R-HSA-9007751] RUNX2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9007819] Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX2 binds HAND2
output	[Complex:R-HSA-9007811] RUNX2:HAND2 [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-9007999] RUNX2 translocates to the nucleus - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9007816
summation	[Summation:9007841] Based on studies in mice, RUNX2 binds to the basic helix-loo...

(hasEvent)	[Pathway:R-HSA-8878166] Transcriptional regulation by RUNX2
(inferredTo)	[Reaction:R-MMU-9007813] Runx2 binds Hand2

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