Reactome | NCoR/SMRT complex [nucleoplasm]

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NCoR/SMRT complex [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9853307] p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:ACSS3 gene:nucleosomes [nucleoplasm] - Homo sapiens [Complex:R-HSA-9864569] PPARG:RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm] - Homo sapiens [Complex:R-HSA-9906911] Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci - Homo sapiens [Reaction:R-HSA-8986939] MECP2 binds the NCoR/SMRT complex - Homo sapiens [FailedReaction:R-HSA-9005585] MECP2 mutants P302R,K304E,K305R,R306C,(R306H) do not bind NCoR/SMRT complex - Homo sapiens
created	[InstanceEdit:9005705] Orlic-Milacic, Marija, 2017-05-09
dbId	9005706
deleted	[Deleted:9919072] Deletion of instance: 9851469
displayName	NCoR/SMRT complex [nucleoplasm]
hasMember	[Complex:R-HSA-9005550] NCOR1 complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-9005701] NCOR2 complex [nucleoplasm] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-9005706] NCoR/SMRT complex [nucleoplasm] - Mus musculus [DefinedSet:R-RNO-9005706] NCoR/SMRT complex [nucleoplasm] - Rattus norvegicus [DefinedSet:R-CFA-9005706] NCoR/SMRT complex [nucleoplasm] - Canis familiaris [DefinedSet:R-BTA-9005706] NCoR/SMRT complex [nucleoplasm] - Bos taurus [DefinedSet:R-SSC-9005706] NCoR/SMRT complex [nucleoplasm] - Sus scrofa [GenomeEncodedEntity:R-DRE-9005706] Ghost homologue of NCoR/SMRT complex [nucleoplasm] - Danio rerio [DefinedSet:R-GGA-9005706] NCoR/SMRT complex [nucleoplasm] - Gallus gallus [DefinedSet:R-DME-9005706] NCoR/SMRT complex [nucleoplasm] - Drosophila melanogaster
literatureReference	[LiteratureReference:3772052] Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery [LiteratureReference:4663828] Nuclear hormone receptor co-repressors: structure and function
maxDepth	6
modified	[InstanceEdit:9005714] Orlic-Milacic, Marija, 2017-05-09
name	NCoR/SMRT complex
producedByEvent	[Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens [Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9005706

Referrals

(hasComponent)	[Complex:R-HSA-9864569] PPARG:RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864568] PPARG:RXRA:NCoR/SMRT:LIPE gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864571] PPARG:RXRA:NCoR/SMRT:FABP4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9853307] p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:ACSS3 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864570] PPARG:RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864573] PPARG:RXRA:NCoR/SMRT:PNPLA2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864572] PPARG:RXRA:NCoR/SMRT:ADIPOQ gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864575] PPARG:RXRA:NCoR/SMRT:AGPAT2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864574] PPARG:RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864563] PPARG:RXRA:NCoR/SMRT:LPL gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864565] PPARG:RXRA:NCoR/SMRT:CD36 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864564] PPARG:RXRA:NCoR/SMRT:CIDEC gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864567] PPARG:RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864566] PPARG:RXRA:NCoR/SMRT:CEBPA gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9853313] p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:THRSP gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864577] PPARG:RXRA:NCoR/SMRT:MGLL gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9853312] p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:SCD5 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864576] PPARG:RXRA:NCoR/SMRT:SCD gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864579] PPARG:RXRA:NCoR/SMRT:PLIN2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9853315] p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864578] PPARG:RXRA:NCoR/SMRT:PLIN1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9853314] p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:ELOVL5 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864581] PPARG:RXRA:NCoR/SMRT:PEX11A gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864580] PPARG:RXRA:NCoR/SMRT:ANGPTL4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864583] PPARG:RXRA:NCoR/SMRT:PPARG gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864582] PPARG:RXRA:NCoR/SMRT:PLIN4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864617] Ligand-bound PPARG:RXRA:NCoR/SMRT:CEBPA gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864616] Ligand-bound PPARG:RXRA:NCoR/SMRT:SCD gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864619] Ligand-bound PPARG:RXRA:NCoR/SMRT:MGLL gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864618] Ligand-bound PPARG:RXRA:NCoR/SMRT:CIDEC gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864621] Ligand-bound PPARG:RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864620] Ligand-bound PPARG:RXRA:NCoR/SMRT:PLIN4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864623] Ligand-bound PPARG:RXRA:NCoR/SMRT:PPARG gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864622] Ligand-bound PPARG:RXRA:NCoR/SMRT:PNPLA2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864609] Ligand-bound PPARG:RXRA:NCoR/SMRT:CD36 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864608] Ligand-bound PPARG:RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864611] Ligand-bound PPARG:RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864610] Ligand-bound PPARG:RXRA:NCoR/SMRT:PLIN1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864612] Ligand-bound PPARG:RXRA:NCoR/SMRT:FABP4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864615] Ligand-bound PPARG:RXRA:NCoR/SMRT:LIPE gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864614] Ligand-bound PPARG:RXRA:NCoR/SMRT:ANGPTL4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864625] Ligand-bound PPARG:RXRA:NCoR/SMRT:LPL gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864624] Ligand-bound PPARG:RXRA:NCoR/SMRT:AGPAT2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864627] Ligand-bound PPARG:RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864626] Ligand-bound PPARG:RXRA:NCoR/SMRT:ADIPOQ gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864629] Ligand-bound PPARG:RXRA:NCoR/SMRT:PLIN2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864628] Ligand-bound PPARG:RXRA:NCoR/SMRT:PEX11A gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906896] Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:ELOVL5 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9005564] MECP2:NCoR/SMRT complex [nucleoplasm] [Complex:R-HSA-9864662] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PLIN2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864663] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864660] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:LPL gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864661] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:MGLL gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864658] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:CIDEC gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864659] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PNPLA2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864656] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:CEBPA gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864657] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:CD36 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864670] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906911] Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906910] Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:ACSS3 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864671] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:LIPE gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864668] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:SCD gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906909] Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:THRSP gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864669] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:ADIPOQ gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906908] Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:SCD5 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864666] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PEX11A gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864667] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PPARG gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864664] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:AGPAT2 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864665] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:FABP4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864655] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864652] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864653] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:ANGPTL4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906913] Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:ELOVL5 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864672] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PLIN1 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9864673] Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PLIN4 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906901] Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:ACSS3 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906900] Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:SCD5 gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906899] Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:THRSP gene:nucleosomes [nucleoplasm] [Complex:R-HSA-9906898] Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm]
(input)	[Reaction:R-HSA-9843115] Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci [Reaction:R-HSA-8986939] MECP2 binds the NCoR/SMRT complex [FailedReaction:R-HSA-9005585] MECP2 mutants P302R,K304E,K305R,R306C,(R306H) do not bind NCoR/SMRT complex
(output)	[Reaction:R-HSA-9843117] Corepressors are released from liganded PPARG:RXRA heterodimer
(replacementInstances)	[Deleted:9919072] Deletion of instance: 9851469

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