Reactome | SAMD8 transfers phosphatidyl from PE onto C16DH CER

Schema > Reaction > Entries

SAMD8 transfers phosphatidyl from PE onto C16DH CER Show undefined attributes

authored	[InstanceEdit:8959465] Jassal, Bijay, 2017-01-26
catalystActivity	[CatalystActivity:8959466] ceramide phosphoethanolamine synthase activity of SAMD8 trimer [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:8959465] Jassal, Bijay, 2017-01-26
crossReference	[DatabaseIdentifier:12667867] RHEA:42128
dbId	8959462
displayName	SAMD8 transfers phosphatidyl from PE onto C16DH CER
edited	[InstanceEdit:8959465] Jassal, Bijay, 2017-01-26
eventOf	[Pathway:R-HSA-1660661] Sphingolipid de novo biosynthesis - Homo sapiens
input	[SimpleEntity:R-ALL-9843232] C16DH CER [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-9843247] PE [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8959484] Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER [LiteratureReference:9843239] Ceramide phosphoethanolamine, an enigmatic cellular membrane sphingolipid [LiteratureReference:9843231] ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SAMD8 transfers phosphatidyl from PE onto C16DH CER
orthologousEvent	[Reaction:R-PFA-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Plasmodium falciparum [Reaction:R-CEL-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Caenorhabditis elegans [Reaction:R-DME-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Drosophila melanogaster [Reaction:R-XTR-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Xenopus tropicalis [Reaction:R-DRE-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Danio rerio [Reaction:R-SSC-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Sus scrofa [Reaction:R-BTA-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Bos taurus [Reaction:R-CFA-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Canis familiaris [Reaction:R-RNO-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Rattus norvegicus [Reaction:R-MMU-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Mus musculus
output	[SimpleEntity:R-ALL-8959463] CPE [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-1500596] DAG [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-428259] DEGS1 dehydrogenates dihydroceramide - Homo sapiens
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8959643] D'Eustachio, Peter, 2017-01-30 [InstanceEdit:9851344] D'Eustachio, Peter, 2023-10-24
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8959462
summation	[Summation:8959488] Sphingolipids such as sphingomyelin (SM) are essential compo...
updateTrackers	[UpdateTracker:9853287] Update Tracker - [Reaction:8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - v87:[addLiteratureReference, addOutput, add_removeInput, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9853287] Update Tracker - [Reaction:8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - v87:[addLiteratureReference, addOutput, add_removeInput, modifyText]
(hasEvent)	[Pathway:R-HSA-1660661] Sphingolipid de novo biosynthesis