Reactome | SAMD8 transfers phosphatidyl from PE onto C16DH CER

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SAMD8 transfers phosphatidyl from PE onto C16DH CER Show undefined attributes

catalystActivity	[CatalystActivity:10428595] ceramide phosphoethanolamine synthase activity of SAMD8 trimer [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10428597
displayName	SAMD8 transfers phosphatidyl from PE onto C16DH CER
eventOf	[Pathway:R-BTA-1660661] Sphingolipid de novo biosynthesis - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER - Homo sapiens
input	[SimpleEntity:R-ALL-9843232] C16DH CER [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-9843247] PE [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	SAMD8 transfers phosphatidyl from PE onto C16DH CER
output	[SimpleEntity:R-ALL-8959463] CPE [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-1500596] DAG [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-BTA-428259] DEGS1 dehydrogenates dihydroceramide - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8959462
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-1660661] Sphingolipid de novo biosynthesis
(inferredTo)	[Reaction:R-HSA-8959462] SAMD8 transfers phosphatidyl from PE onto C16DH CER

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