Reactome | ITCH gene expression is stimulated by RUNX1 and YAP1

Schema > BlackBoxEvent > Entries

ITCH gene expression is stimulated by RUNX1 and YAP1 Show undefined attributes

authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:8956651] Orlic-Milacic, Marija, 2017-01-23
dbId	8956652
displayName	ITCH gene expression is stimulated by RUNX1 and YAP1
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
eventOf	[Pathway:R-HSA-8939236] RUNX1 regulates transcription of genes involved in differentiation of HSCs - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8954671] ITCH gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8956643] A regulatory circuit controlling Itch-mediated p73 degradation by Runx
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ITCH gene expression is stimulated by RUNX1 and YAP1
output	[EntityWithAccessionedSequence:R-HSA-975995] ITCH [cytosol]
precedingEvent	[Reaction:R-HSA-8956649] The complex of RUNX1 and YAP1 binds the ITCH gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-8956672] Positive gene expression regulation by 'RUNX1:CBFB:YAP1:ITCH gene [nucleoplasm]'
regulationReference	[RegulationReference:9641663] Positive gene expression regulation by 'RUNX1:CBFB:YAP1:ITCH gene [nucleoplasm]' A regulatory circuit controlling Itch-mediated p73 degradation by Runx
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-8956652
summation	[Summation:8956653] Expression of the ITCH gene, encoding the E3 ubiquitin-prote...

Referrals

(hasEvent)

[Pathway:R-HSA-8939236] RUNX1 regulates transcription of genes involved in differentiation of HSCs

Cite Us!