Reactome | Nucleotide catabolism

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Nucleotide catabolism Show undefined attributes

authored	[InstanceEdit:73784] Jassal, B, 2003-06-26 04:06:16
created	[InstanceEdit:8956325] D'Eustachio, Peter, 2017-01-20
dbId	8956319
diseasePathways	[Pathway:R-HSA-9735763] Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine - Homo sapiens
displayName	Nucleotide catabolism
edited	[InstanceEdit:165072] D'Eustachio, P, Gillespie, ME, Joshi-Tope, G, 0000-00-00 00:00:00
eventOf	[Pathway:R-HSA-15869] Metabolism of nucleotides - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:376473] nucleobase-containing small molecule catabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-74259] Purine catabolism - Homo sapiens [Pathway:R-HSA-73621] Pyrimidine catabolism - Homo sapiens [Pathway:R-HSA-8850843] Phosphate bond hydrolysis by NTPDase proteins - Homo sapiens [Reaction:R-HSA-8866601] SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2021-12-08
literatureReference	[LiteratureReference:84017] Beta-amino acids: mammalian metabolism and utility as alpha-amino acid analogues [LiteratureReference:909759] Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver [LiteratureReference:1442513] Molecular variation in relation to purine metabolism
maxDepth	4
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Nucleotide catabolism
orthologousEvent	[Pathway:R-RNO-8956319] Nucleotide catabolism - Rattus norvegicus [Pathway:R-DRE-8956319] Nucleotide catabolism - Danio rerio [Pathway:R-BTA-8956319] Nucleotide catabolism - Bos taurus [Pathway:R-PFA-8956319] Nucleotide catabolism - Plasmodium falciparum [Pathway:R-SCE-8956319] Nucleotide catabolism - Saccharomyces cerevisiae [Pathway:R-SPO-8956319] Nucleotide catabolism - Schizosaccharomyces pombe [Pathway:R-DDI-8956319] Nucleotide catabolism - Dictyostelium discoideum [Pathway:R-CEL-8956319] Nucleotide catabolism - Caenorhabditis elegans [Pathway:R-DME-8956319] Nucleotide catabolism - Drosophila melanogaster [Pathway:R-GGA-8956319] Nucleotide catabolism - Gallus gallus [Pathway:R-XTR-8956319] Nucleotide catabolism - Xenopus tropicalis [Pathway:R-SSC-8956319] Nucleotide catabolism - Sus scrofa [Pathway:R-CFA-8956319] Nucleotide catabolism - Canis familiaris [Pathway:R-MMU-8956319] Nucleotide catabolism - Mus musculus
releaseDate	2004-07-06
releaseStatus	UPDATED
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:165071] Graves, L, Rush, MG, 0000-00-00 00:00:00
revised	[InstanceEdit:8956493] D'Eustachio, Peter, 2017-01-23
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-8956319
summation	[Summation:8956450] The purine bases guanine and hypoxanthine (derived from aden...
updateTrackers	[UpdateTracker:9776310] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v76:[updateContainedPathway] [UpdateTracker:9776180] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v77:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9775763] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v78:[updateContainedPathway, updateContainedRLE, updateIndirectRLE] [UpdateTracker:9781043] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v61:[updateIndirectRLE] [UpdateTracker:9775402] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v79:[updateIndirectRLE]

Referrals

(updatedInstance)	[UpdateTracker:9776310] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v76:[updateContainedPathway] [UpdateTracker:9776180] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v77:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9775763] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v78:[updateContainedPathway, updateContainedRLE, updateIndirectRLE] [UpdateTracker:9781043] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v61:[updateIndirectRLE] [UpdateTracker:9775402] Update Tracker - [Pathway:8956319] Nucleotide catabolism - v79:[updateIndirectRLE]
(normalPathway)	[Pathway:R-HSA-9735763] Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine
(hasEncapsulatedEvent)	[Pathway:R-HSA-71336] Pentose phosphate pathway
(hasEvent)	[Pathway:R-HSA-15869] Metabolism of nucleotides

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